blake image

Charles A. Blake, Ph.D., FAAA

Distinguished Professor of Cell Biology & Anatomy
University of South Carolina School of Medicine
Office:  803-216-3801
Lab:     803-216-3830
Fax:     803-216-3846
PubMed Link:


Brown University – Bachelors of Arts – Biology

University of Houston – Masters of Science – Physiology 
    University of California, Los Angeles – Ph.D. – Anatomy

Research Focus:

Dr. Blake's research focuses on neuroendocrine control of female reproductive cycles, disruptive effects of environmental pollutants on endocrine and reproductive processes, and hypothalamic hormone and gonadal steroid control of the anterior pituitary gland proteome.

Recent Publications

  • Blake CA, McCoy GL, Hui YY, LaVoie HA. Perinatal exposure to low-dose DE-71 increases serum thyroid hormones and gonadal osteopontin gene expression. Exp Biol Med. 2011 Apr 1; 236(4):445-55. Epub 2011 Mar 2.
  • Blake CA, Sobel BE. Progress in pharmacogenomics and its promise for medicine. Exp Biol Med 2008 Dec; 233(12):1482-3. Epub 2008 Oct 10.
  • Benoit AM, LaVoie HA, McCoy GL, Blake CA. Expression of sperm protein 22 (SP22) in the rat ovary during different reproductive states. Exp Biol Med (2007 Jul; 232(7):910-20.
  • Blake CA, Barker KL, Sobel BE. The role of modern biology and medicine in drug development in academia and industry. Exp Biol Med2006 Dec; 231(11):1680-1.
  • Goodman SR, Blake CA. The future of interdisciplinary research and training: how to conquer the silo guardians. Exp Biol Med 2006 Jul; 231(7):1189-91.
  • West JR, Blake CA. Fetal alcohol syndrome: an assessment of the field. Exp Biol Med 2005 Jun; 230(6):354-6.
  • Blake CA, Kakhniashvili DG, Goodman SR. Mouse anterior pituitary gland: analysis by ion trap mass spectrometry. Neuroendocrinology. 2005; 81(4):229-43. Epub 2005 Aug 10.
  • Benoit AM, McCoy GL, Blake CA. Localization of fertility factor SP22 to specific cell types within the anterior pituitary gland. Exp Biol Med 2005 Nov; 230(10):721-30.
  • Blake CA, Helmke SM. Proteomics of the anterior pituitary gland as a model for studying the physiology of a heterogeneous organ. Exp Biol Med 2005 Dec; 230(11):793-9.
  • Blake CA, Brown LM, Duncan MW, Hunsucker SW, Helmke SM. Estrogen regulation of the rat anterior pituitary gland proteome. Exp Biol Med 2005 Dec; 230(11):800-7.
  • Blake CA, Kakhniashvili DG, Goodman SR.  Analysis of the golden Syrian hamster anterior pituitary gland proteome by ion trap mass spectrometry.Neuroendocrinology. 2004; 80(6):355-67.