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Mary F. Forman, Ph.D.


Title:

Research Associate Professor

PUBMED Link:

Forman MF

Research:

Cardiac Mast Cell Biology: Phenotypic alterations in cardiac mast cells during sustained ventricular volume overload.
  • Mast Cell Origin.
  • Mast Cell Maturation, Proliferation, and Migration.
  • Role of Stem Cell Factor during sustained volume overload.

Long-Term Ventricular Tissue Slice Cultures: Currently developing ventricular slice cultures to model cardiac disease.


Recent Publications:

Forman, M.F., Brower, G.L., and J. S. Janicki. Rat Cardiac Mast Cell Maturation and Differentiation Following Acute Ventricular Volume Overload. Inflammation Research (In Press).

Janicki JS, Brower GL, Gardner JD, Forman MF, Stewart Jr JA, Murray DB, and Chancey AL. Regulation of myocardial matrix metalloproteinases in mediating the ventricular remodeling response to sustained volume or pressure overload. Cardiovascular Res. 69:657-665, 2006.

Janicki, J.S., Brower, G.L., Chancey, A.L., Forman, M.F., and L.J., Jobe. Cardiac mast cells as mediators of ventricular remodeling. In, Intersitial Fibrosis in Heart Failure. FJ Villarreal (ed), Springer, New York. Pp. 197-209, 2004.

Forman, M.F., Brower, G.L., and J. S. Janicki. 2004. Spontaneous histamine secretion occurs during isolation of rat cardiac mast cells. Inflamm. Res. 53:453-457, 2004.

Janicki, J.S., Brower, G.L., Carver, W., Chancey, A.L., Forman, M.F., and L.J., Jobe. Role of mast cells in cardiovascular disease. In, Cardiovascular Remodeling and Failure. P.K. Singal, I.M.C. Dixon, L.A. Kirschenbaum, N.S. Dhalla (eds), Kluwer Academic Publishers, Boston. pp. 485-499, 2002.

de Almeida, A., Mustin, D., Forman, M.F., Brower, G.L., J.S. Janick, and W. Carver. Effects of mast cells on the behavior of isolated heart fibroblasts: Modulation of collagen remodeling and gene expression. J. Cell. Physiol. 191: 51-9, 2002.

Forman, M.F., and R.F.Wideman, Jr. Furosemide does not facilitate pulmonary vasodilation in broilers during acute or chronic unilateral pulmonary arterial occlusion. Poultry Sci. 80:937-943, 2001.

Forman, M. F., and R. F. Wideman, Jr. Measurements of pulmonary arterial pressure in anesthetized male broilers at two to seven weeks of age. Poultry Sci 79:1645-1649, 2000.



Education:


Contact Information:

mforman@gw.med.sc.edu
(803)-733-3304 (Office)
(803)-733-3396 (Lab)


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