Faculty Name:
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Shekhar Patel, Ph.D.
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Title:
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| Research Assistant Professor |
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PUBMED Link:
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Research:
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Molecular regulation of vascular endothelial and smooth muscle cells. |
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Recent Publications:
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- Marc S. Penn, Chandrashekhar V. Patel, Mei Zhen Cui, Paul E. DiCorleto and Guy M.
Chisholm (1999) LDL increases inactive tissue factor on vascular smoth muscle cell
surfaces; hydrogen peroxide activates latent cell surface tissue factor. Circulation 99,
1753-1759.
- Chandrashekhar V. Patel, Rajesh Sharangpani and Paul E. DiCorleto (1999) Endothelial
cells express a novel TNF-alpha regulated varient of HOXA9. J. Biol. Chem. 274, 1415-1422.
- Chandrashekhar V. Patel, Indhira Handy, Tiffany Goldsmith, and Rekha C. Patel (2000)
PACT, a stress-modulated cellular activator of interferon-induced double-stranded
RNA-activated protein kinase, PKR. J. Biol. Chem. 275, 37993-37998.
- Rekha C. Patel, Indhira Handy, and Chandrashekhar V. Patel (2002) Contribution of
double-stranded RNA-activated protein kinase toward antiproliferative actions of heparin
on vascular smooth muscle cells.
- Arterioscler. Thromb. Vasc. Biol. 221, 439-1444.
- Steven Fasciano, Rekha C. Patel, Indhira Handy, and Chandrashekhar V. Patel (2005)
Regulation of vascular smooth muscle proliferation by heparin: Inhibition of
cyclin-dependent kinase activity by p27kip1. J. Biol. Chem. 280(16),15682-15689.
- Chinmay Trivedi, Rekha C. Patel, and Chandrashekhar V. Patel (2006) Homeobox gene HOXA9
inhibits nuclear factor-kappaB dependent activation of endothelium. J. Biol. Chem. (under
revision for re-submission).
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Education:
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- Gujrat State University B.S. 1979 Microbiology
- M. S. University of Baroda ( Baroda, India ) M.S. 1981 Microbiology
- Indian Institute of Science ( Bangalore, India) Ph.D. 1987 Molecular Biology
- Case Western Reserve University ( Cleveland, USA) Post-Doc 1987-1990 Molecular Biology
- Case Western Reserve University ( Cleveland, USA) Res. Ass. 1990-1993 Molecular Biology
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Contact Information:
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Chandrashekhar V. Patel
Email: patelc@gw.med.sc.edu
Phone: 803-733-3274
Address: Building 4 Room C-11
USC School of Medicine
Columbia, SC 29209
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