J.D. Potts, Ph.D.

Jay D. Potts, Ph.D.

Professor of Cell Biology & Anatomy
University of South Carolina School of Medicine

Contact:
Office: 803-216-3820
Lab:    803-216-3838
Fax:     803-216-3846
Email: jay.potts@uscmed.sc.edu

Pubmed

1982-1986 Wartburg College – Bachelors of Arts, Biology & Chemistry
1987-1991 University of Iowa – Ph.D. – Anatomy & Cell Biology

Research Focus

The focus of the Potts lab is to use the principles of developmental biology and marriage it to regenerative medicine. Millions of people suffer from a vast assortment of diseases and complications that are now treated with new regenerative medicine therapies. The goal of the lab’s research is to develop biocompatible tissues and treatments for numerous diseases and pathologies. Heart valves, cartilage, bone, cornea and wound healing are examples of the tissues our lab studies. Furthermore, we have incorporated the use of mesenchymal stem cells, which provide the necessary cellular component to create these in vitro constructs. As a result, the development of biocompatible tissues using the host’s own cells will be designed and created to help repair and remodel various defects.

Recent Publications

  • Menon, V, Eberth, JF, Goodwin, RL., Potts, JD., 2015 Altered Hemodynamics in the Embryonic Heart Affects Outflow Valve Development. J. Card Develop and Disease. 2; 108-124.
  • Menon, V, Junor, L, Belhaj, M., Eberth, JF., Potts, JD., 2016. A novel ex ovo banding technique to alter intracardiac hemodynamics in an embryonic chicken system. J Vis Exp. 2016 May 13;(111). doi: 10.3791/53955. PMID: 27213265
  • Valarmathi, MT, Fuseler, JW, Potts, JD, Davis, JM, Price, RL. 2017. Functional Tissue‐Engineering: A Prevascularized Cardiac Muscle Construct for Validating hMSCs Engraftment Potential in Vitro. Biomaterials. DOI: 10.1089/ten.TEA.2016.0539
  • Menon, V., Ebertj. JF., Junor, L., Potts, AJ., Belhaj, M., Dipette, DJ., Jenkins, MW., Potts, JD., 2017. Removing vessel constriction on the embryonic heart results in changes in valve gene expression, morphology, and hemodynamics. Dev. Dynamics. DOI: 10.1002 dvdy.24588
  • Balasubramaniam, A., Parsons, N., Belhaj, M., Carlene, B., Potts, JD, Rohrer, B. 2017. Encapsulated cell technology-based delivery of a complement inhibitor reduces choroidal neovascularization in a mouse model. Translational Vision Science & Technology (In Press)
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